Post-pandemic geopolitical dynamics have significantly changed the global landscape. The COVID-19 pandemic has accelerated pre-existing trends and created new challenges for countries around the world. One of the main impacts is the emergence of a focus on economic independence. Many countries are recognizing their dependence on fragile global supply chains, prompting efforts to strengthen domestic industries. Furthermore, long lockdowns and travel restrictions have accelerated the development of digitalization. Countries are now more open to new technologies, and the adoption of digital technologies in government and the business sector is increasing. In addition, countries that have good digital infrastructure are able to overcome the impact of the pandemic better than those that don’t. This transformation has had a new impact on international relations, because countries that are able to adapt quickly tend to have greater influence. In a geopolitical context, tensions between major powers such as the United States and China are increasingly visible. Competition in technology and global health, especially in vaccine development, shows how the pandemic is exacerbating strategic rivalries. China’s vaccine diplomacy tactics, for example, are becoming a tool to expand influence in developing countries, changing traditional geopolitical dynamics. This raises questions about the global primacy between geopolitics and public health. Climate change is also increasingly high on the agenda in post-pandemic geopolitics. With increasing awareness of climate change, countries are seeking to align their foreign policies with commitments to reduce carbon emissions. The rise of renewable energy and the shift away from fossil fuels is the main focus of countries with ambitions to achieve emissions targets. For example, the European Union underscored the importance of Green Deal policies as a strategy to lead the global energy transition. The situation in the Middle East region continues to be volatile, with the consequences of the pandemic exacerbating existing conflicts. Countries such as Iran and Saudi Arabia seek to strengthen their position in the regional context, while intervention by great powers often complicates the dynamics. Meanwhile, the conflict in Afghanistan following the withdrawal of US troops shows the long-term impact of geopolitical decisions related to domestic health and security. Simultaneously, populist and nationalist movements that have emerged during the pandemic are influencing domestic policies in many countries. Dissatisfaction with political elites and global institutions has created challenges for multilateral cooperation. Many countries now prefer a unilateral approach, which has the potential to undermine global efforts to address pressing issues such as public health and environmental issues. In terms of security, cyber threats have increased tremendously during the pandemic. Many countries are facing coordinated cyber attacks, increasing the shift in focus to cybersecurity as a key component in diplomacy. Investment in cybersecurity infrastructure is now a priority, creating new agreements and cooperation between countries to counter threats in the digital world. Finally, the issue of migration due to the pandemic also deserves attention. Strict travel restrictions have created unique migration flows, with varying impacts on the politics of destination countries. Countries that previously relied on migrant labor must now adapt policies to respond to new challenges and opportunities. Some countries are actually tightening immigration policies, while others see it as an opportunity for economic revitalization.